Drew Gilbert's two-run homer in the 10th lifts Giants to a 6-5 win over the Cardinals
San Francisco Giants' Drew Gilbert, right, is congratulated by teammate Grant McCray (58) after hitting a two-run home run during the 10th inning of a baseball game against the St. Louis Cardinals Wednesday, Sept. 16, 2026, in St. Louis. Credit: AP/Jeff Roberson
ST. LOUIS — Drew Gilbert hit a two-run home run in the 10th inning, lifting the San Francisco Giants to a 6-5 victory over the St. Louis Cardinals on Wednesday afternoon.
Gilbert’s first home run came off Riley O’Brien (3-9) and scored Grant McCray, who was on second.
The Giants improved to 7-6 in extra-inning games; the Cardinals dropped to 8-8.
Reiver Sanmartín (3-0) earned the win after getting the final out in the ninth. Joel Kuhnel picked up his eighth save despite giving up a sacrifice fly to Thomas Saggese.
Jonah Cox had three hits and two stolen bases. He also scored a run and drove in a run, helping the Giants win the three-game series.
Andrew Kizner added three hits and drove in a run for San Francisco.
The Cardinals fought back in the ninth with two runs off Dylan Smith, who blew his fifth save. Nolan Gorman drew a leadoff walk and Saggese reached on an infield single. With one out, pinch hitter Iván Herrera walked. José Fermín's sacrifice fly drove in a run and Leo Bernal’s single made it 4-4.
St. Louis Cardinals' Thomas Saggese, left, reaches base on an error by San Francisco Giants pitcher Carson Seymour during the seventh inning of a baseball game Wednesday, Sept. 16, 2026, in St. Louis. Credit: AP/Jeff Roberson
Anthony Molina pitched 5 2/3 shutout innings before leaving after throwing 82 pitches.
Left-hander Matthew Liberatore allowed one run in six innings.
San Francisco extended its lead to 3-0 in the seventh against Luis Gastelum. Kizner was hit by a pitch and Christian Kross singled with one out. Cox then singled to right. Jordan Walker’s throw eluded Gorman at third base, allowing Kross to score.
The Giants went up 1-0 in the third inning. Brett Harris grounded into a double play, but Cox scored from third.
St. Louis Cardinals right fielder Jordan Walker catches a fly ball by San Francisco Giants' Christian Koss during the fifth inning of a baseball game Wednesday, Sept. 16, 2026, in St. Louis. Credit: AP/Jeff Roberson
Walker recorded his first 20-20 season, stealing his career-high 20th base in the fourth inning. He has also hit a career-high 28th home run.
Up next
Giants: Off Thursday. LHP Cesar Perdomo (0-1, 3.68) will face a Dodgers starter to be announced Friday in Los Angeles.
Cardinals: Off Thursday. RHP Kyle Leahy (10-4, 3.33) will face Washington. The visiting Nationals have not announced a starter.
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